科研团队：仿生材料与组织工程研究团队
团队网站：https://www.x-mol.com/groups/BMTEers
一、团队研究方向：
金沙9170“仿生材料与组织工程研究”团队的主要研究方向为：1. 临床生物医用材料与体外诊断试剂的研发；2. 功能复合材料；3. 仿生材料与组织工程；4. 药物可控缓释系统。团队围绕材料学、细胞与分子生物学、临床医学等多学科交叉，以仿生生物医用材料为工具重点探索支架与（干）细胞/组织相互作用机制、疾病诊断、药物可控释放系统、再生医学方面的基础和应用研究。
二、团队负责人简介
袁卉华博士, 副教授（校聘教授）, 硕士生导师。江苏省“六大人才高峰”高层次人才培养对象。在生物材料、纳米技术、高分子复合材料等领域的学术刊物上发表SCI论文38篇（其中以第一或通讯作者发表SCI论文20篇，JCR一区论文8篇，二区论文6篇），获选SCI 期刊编辑的重点推荐（Editor’s Pick）及特色文章（Featured articles）1篇（Biomed Mater 2014, 9(5):055001），目前SCI论文被引用达1500余次，H-指数22（谷歌学术数据），第一作者撰写英文专著的1个章节，获授权5项中国发明专利。现任Frontiers in Bioengineering and Biotechnology期刊（IF= 5. 89, 二区）客座编辑，是中国生物材料学会、中国生物医学工程学会、中国化学会会员以及国际组织工程与再生医学会员，也是Adv Sci, Small等一区TOP国际学术期刊的受邀论文评审人。近年来，承担国家自然科学青年基金项目、江苏省自然科学青年基金项目、南通市科技计划项目等10项课题。
三、团队成员
教师
李碧云 博士、高级实验师
瞿建刚 博士、副教授
薛也 博士、讲师（校聘副教授）
宣红云 博士、讲师
研究生
熊峰、吴淑嫄、杜茜、魏硕、张卓君、刘向艳
本科生
蒋伟、童心、高晓晓、黄泽鹏、卜嘉森、黄宇婷、杨舒文、华馨丽、李念慈、李瑞萌、孙莉、孙芸倩、王左阳、吴怡佳、圣涵、韩翔、崔文卓、刘子豪
四、科研项目
2019-2021: 国家自然科学基金-青年项目：肌腱再生（袁卉华）
2021-2023: 国家自然科学基金-青年项目：神经再生（宣红云）
2020-2023: 江苏省自然科学基金-青年基金项目：神经再生（宣红云）
2018-2021: 江苏省自然科学基金-青年基金项目：肌腱再生（袁卉华）
2018-2020: 江苏省“六大人才高峰”高层次人才项目：肌腱再生（袁卉华）
2018-2020: 江苏省产学研合作项目：纺织（瞿建刚）
2016-2018: 江苏省高校自然科学研究面上项目：光催化（瞿建刚）
2020-2023: 江苏省高校自然科学研究面上项目：神经再生（宣红云）
2019-2020: 纺织面料技术教育部重点实验室开放基金项目：光热转化（瞿建刚）
2021-2023: 南通市科技项目：神经再生（薛也）
2019-2021: 南通市科技项目：气管软骨再生（李碧云）
2019-2021: 南通市科技项目：神经再生（宣红云）
2019-2021: 南通市科技项目：光热转化（瞿建刚）
2017-2019: 南通市科技项目：肌腱再生（袁卉华）
2016-2018: 南通市科技项目：光催化（瞿建刚）
五、近5年主要论文及著作
Feng Xiong, Shuo Wei, Han Sheng, Xiang Han, Wei Jiang, Zhuojun Zhang, Biyun Li, Hongyun Xuan, Ye Xue*, Huihua Yuan*.In situ polydopamine functionalized poly-L-lactic acid nanofibers with near-infrared-triggered antibacterial and reactive oxygen species scavenging capability.International Journal of Biological Macromolecules, 2022, 201:338-350.
Xiaolei Li#, Feng Xiong#, Shuguang Wang, Zhuojun Zhang, Jihang Dai, Hui Chen, Jingcheng Wang, Qiang Wang*, Huihua Yuan*.N-acetyl-cysteine-loaded biomimetic nanofibrous scaffold for osteogenesis of induced-pluripotent-stem-cell-derived mesenchymal stem cells and bone regeneration. Frontiers in Bioengineering and Biotechnology, 2021, 9:767641.
Hongyun Xuan#, Shuo Wei#, Feng Xiong, Zhuojun Zhang, Ye Xue, Miao Sun*, Biyun Li*, Huihua Yuan*. Design of porous and fish scale-like nanofibers for the reinforcement of transparent composites. Materials & Design, 2021, 212:110284.
Cong Gao, Shuai Lu, Yongzhou Wang, Hao Xu, Xiaoxiao Gao, Yiwen Gu, Hongyun Xuan, Baohua Wang*, Huihua Yuan* , Yunying Cao*. Bismuth vanadium oxide can promote growth and activity in Arabidopsis thaliana. Frontiers in Chemistry, 2021, 9:766078.
Hongyun Xuan, Shuyuan Wu, Simiao Fei, Biyun Li, Yumin Yang*, Huihua Yuan*. Injectable nanofiber-polysaccharide self-healing hydrogels for wound healing. Materials Science & Engineering C, 2021, 128: 112264.
Biyun Li, Shuo Wei, Hongyun Xuan, Ye Xue, Huihua Yuan*. Tailoring fineness and content of nylon-6 nanofibers for reinforcing optically transparent poly(methyl methacrylate) composites. Polymer Composites, 2021, 1-10.
Hongyun Xuan#, Biyun Li#, Feng Xiong, Shuyuan Wu, Zhuojun Zhang, Yumin Yang*, Huihua Yuan*. Tailoring nano-porous surface of aligned electrospun poly(L-lactic acid) fibers for nerve tissue engineering. International Journal of Molecular Science, 2021, 22:3536.
Huihua Yuan#,*, Xiaolei Li#, Ming-Song Lee, Zhuojun Zhang, Biyun Li, Hongyun Xuan, Wan-Ju Li , Yanzhong Zhang*.Collagen and chondroitin sulfate functionalized bioinspired fibers for tendon tissue engineering application. International Journal of Biological Macromolecules, 2021, 170:248-260.
Ye Xue, Krista Jackson, Natalie Page, Xiaoyang Mou, Samuel Lofland, Xiao Hu*. Water-annealing regulated protein-based magnetic nanofiber materials: tuning silk structure and properties to enhance cell response under magnetic fields, Materials Today Chemistry, 2021, 22: 100570.
Biyun Li#, Yinhu Liu#, Shuo Wei, Yuting Huang, Shuwen Yang, Ye Xue, Hongyun Xuan, Huihua Yuan*. A solvent system involved fabricating electrospun polyurethane nanofibers for biomedical applications. Polymers, 2020, 12:3038.
Biyun Li#, Feng Xiong#, Bo Yao, Qian Du, Jun Cao, Jiangang Qu, Wei Feng*, Huihua Yuan*. Preparation and characterization of antibacterial dopamine-functionalized reduced graphene oxide/PLLA composite nanofibers. RSC Advances, 2020,10:18614-18623.
Hongyun Xuan, Xiaoxuan Tang, Yanxi Zhu, Jue Ling*, Yumin Yang*. Freestanding hyaluronic acid/silk-based self-healing coating towards tissue repair with antibacterial surface. ACS Applied Bio-materials, 2020,3(3):1628-1635.
Ye Xue, Sam Lofland, Xiao Hu*. Protein-based flexible thermal conductive materials with continuous network structure: fabrication, properties, and theoretical modeling, Composites Part B Engineering, 2020, 201(49): 108377.
Ye Xue, Sam Lofland, Xiao Hu*. Comparative study of silk-based magnetic materials: effect of magnetic particle types on the protein structure and biomaterial properties, International Journal of Molecular Sciences, 2020, 21(20): 7583.
Ye Xue, Xiao Hu*. Electrospun silk-boron nitride nanofibers with tunable structure and properties, Polymers, 2020, 12(5): 1093.
Hao Chen#, Biyun Li#, Bei Feng, Hao Wang, Huihua Yuan*, Zhiwei Xu*. Tetracycline hydrochloride loaded citric acid functionalized chitosan hydrogel for wound healing. RSC Advances, 2019, 9(34):19523-19530.
Hongyun Xuan, Yanxi Zhu, Jiaoyu Ren, Wei Dai, Liqin Ge*. Self-healing, antibacterial, and dual cross-linked multilayer films for microcapsule-based controllable drug release applications. Applied Surface Science, 2019, 476: 182-188.
Hongyun Xuan, Yanxi Zhu, Jiaoyu Ren, Liqin Ge*. Intrinsic self-healing and biocompatibility of carbon nitride coatings via inhibiting or degrading ethylene for fruit preservation. Journal of materials science, 2019, 54: 9282-9290.
Ye Xue#, Fang Wang#, Maria Torculas, Samuel Lofland, Xiao Hu*. Formic acid regenerated mori, tussah, eri, thai, and muga silk materials: mechanism of self-assembly, ACS Biomaterials Science & Engineering, 2019, 5(12): 6361-6373.
Jiangang Qu, Nanfei He, Shradha V. Patil, Yanan Wang, Debjyoti Banerjee, Wei Gao.Screen printing of graphene oxide patterns onto viscose nonwovens with tunable penetration depth and electrical conductivity. ACS Applied Materials Interfaces, 2019, 11:14944-14951.
Jiangang Qu, Nannan Li, Chunmei Wang, Jinxin He. Study of degradation products and degradation pathways of sulfonated azo dyes under ultraviolet irradiation.Textile Research Journal, 2019, 89(3):322-334.
Hao Chen#, Hao Wang#, Biyun Li#, Bei Feng, Xiaomin He, Wei Fu, Huihua Yuan*, Zhiwei Xu*. Enhanced chondrogenic differentiation of human mesenchymal stems cells on citric acid-modified chitosan hydrogel for tracheal cartilage regeneration applications. RSC Advances, 2018, 8(30): 16910-16917.
Hongyun Xuan, Wei Dai, Yanxi Zhu, Jiaoyu Ren, Jianhao Zhang, Liqin Ge*. Self-Healing, antibacterial and sensing nanoparticle coating and its excellent optical applications. Sensors and actuators B: Chemical, 2018, 257:1110-1117.
Hongyun Xuan, Jiaoyu Ren, Xizhang Wang, Jianhao Zhang, Liqin Ge*. Flame-retardant, non-irritating and self-healing multilayer films with double-network structure. Composites Science and Technology, 2017, 145: 15-23.
Hongyun Xuan, Jiaoyu Ren, Jianhao Zhang, Liqin Ge*. Novel highly-flexible, acid-resistant and self-healing host-guest transparent multilayer films. Applied Surface Science, 2017, 411: 303-314.
Ye Xue, Dave Jao, Wenbing Hu, Xiao Hu*. Silk-silk blend materials, Journal of Thermal Analysis and Calorimetry, 2017, 127(1): 915-921.
Book Chapter
Huihua Yuan#, Qihui Zhou#, Yanzhong Zhang*, 6. Improving fiber alignment during electrospinning, in Electrospun nanofibers, Editor: Mehdi Afshari, Woodhead Publishing, 2017. ISBN: 9780081009079.
六：省优本科毕业论文
2021.09，熊峰，“还原石墨烯/聚乳酸功能复合纳米纤维用于神经组织工程支架的研究”，2020年江苏省普通高校本专科优秀毕业设计（论文）三等奖
七、联系方式以及其它信息
Email: yuanhh@ntu.edu.cn
欢迎感兴趣的青年人才和同学加入！